Abstract
Glutamate induced responses in the surface membrane of Xenopus oocyte by injection with mRNA from crustacea and insect muscle. Glutamate (10 −5 to 10 −4 M) elicited smooth current responses which resembled those induced by kainate. This smooth current reversed direction at about 0 mV and was blocked by a spider toxin (JSTX). Higher concentrations (more than 1 × 10 −3 M) of glutamate induced JSTX-insensitive oscillatory current responses which may be caused by Cl − activation.
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