Abstract
AbstractWistar rats excreted more glucuronides into the urine than Sprague‐Dawley rats, both in the basal state and after oral menthol loading. The liver and kidney of the former strain had higher uridine diphosphate glucose dehydrogenase (UDPG dehydrogenase) and β‐glucuronidase levels than the corresponding organs of the latter strain. Uridine diphosphate glucuronyltransferase (UDP glucuronyltransferase) activity was also higher in the liver of Wistar than of Sprague‐Dawley rats, the situation being opposite in the kidney. The activity of UDP glucuronyltransferase was higher in the liver and kidney of young rats than of adult rats, the response produced by ethylene diamine tetra‐acetic acid (EDTA) in the liver being somewhat dependent on the age and sex of the animals. The activities of phosphatases destroying uridine diphosphate glucuronic acid (UDPGA), measured as the release of inorganic phosphate from UDPGA in the presence and absence of EDTA, differed only slightly in the different groups.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
