Abstract
Fifteen normal subjects were fasted for 3–7 days while undergoing daily sweating in an environmental chamber. Sweat lactate concentration decreased 19% and reached a new steady state by the third day of last. Recovery of 14 C-labeled lactate in sweat after injection of 14 C-labeled glucose was enhanced ruing starvation, suggesting preferential utilization of circulating glucose for sweat gland glycogen content decreased markedly during sweating in fasted subjects nearly complete recovery of normal glycogen content was observed 6 hr after conclusion of sweating. In the sweat gland, significant dependence upon carbohydrate metabolism persists during the fasted state.
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