Abstract
Glucose transporters are the main carriers in the transportation of glucose in mammals; it mediates glucose across cell membranes into cells through facilitated diffusion .Glucose transporter 1 (GLUT1) and glucose transporter 3 (GLUT3)are the two main proteins responsible for the transport of glucose in the brain. Cerebral hypoxia-ischemia may increase the synthesis of GLUT1 and GLUT3 to accelerate the transport and utilization of glucose in the brain and adapt to the requirements of anaerobic glycolysis. These effects caused by cerebral hypoxia -ischemia play an important role in ensuring the brain's energy supply and therefore delay the cascade reaction caused by energy failure. This review mainly focuses on the structures, distributions and functions of GLUT1 and GLUT3 in the brain and influence of cerebral hypoxia-ischemia on their expression and regulation. Key words: Glucose transporters; Cerebral hypoxia-ischemia
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
