Abstract
An enzyme nanosensor, based on a carbon fiber cone nanoelectrode modified by codeposition of Prussian blue (PB) and glucose oxidase (GOD), has been constructed. The nanosensor displays a low-potential electrocatalytic detection of the enzymatically liberated hydrogen peroxide, along with good reproducibility and high selectivity. The dependence of the nanosensor response upon parameters of the sensor preparation (e.g., amount of GOD, PB deposition time, Nafion coverage), and upon measurements conditions (e.g., pH, applied potential) was evaluated. An operating potential of –0.1 V (vs. Ag/AgCl) yielded the highest selectivity towards glucose, with no interference from ascorbic acid. The lifetime of the nanosensor is more than two weeks. Such miniaturization and analytical performance offer great promise for measurements of glucose in extremely small volumes.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
