Abstract
The newborn rat was investigated for the presence of hypoglycaemia during the first hours after birth. Animals were born naturally and were left with the mother until sampled. There was no evidence of hypoglycaemia at birth or over the next 6 h. There was a rise in the blood glucose in the first hour after birth and this was associated with the period of most rapid mobilization of liver glycogen. Plasma immunoreactive insulin (IRI) fell rapidly after birth to values seen in fed adult rats. In contrast to the results obtained from rats born prematurely by Caesarian section, the normal process of birth followed by a normal environment with the mother, allows the newborn rat to maintain its glucose homeostasis.
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