Glucose exposure in vitro stimulates excessive TNFα release from mononuclear cells (MNC) of women with polycystic ovary syndrome (PCOS)

F Gonzalez,J Minium,J.P Kirwan,N.S Rote

doi:10.1016/j.fertnstert.2004.07.842

Glucose exposure in vitro stimulates excessive TNFα release from mononuclear cells (MNC) of women with polycystic ovary syndrome (PCOS)

F Gonzalez, J Minium + Show 2 more

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https://doi.org/10.1016/j.fertnstert.2004.07.842

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Journal: Fertility and Sterility	Publication Date: Sep 1, 2004
License type: publisher-specific-oa

Affiliation: Case Western Reserve University

#Mononuclear Cells Of Women #Polycystic Ovary Syndrome + Show 7 more

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Abstract

We propose that in PCOS, MNC are a source of excess circulating TNFα in response to hyperglycemia. Thus, the effect of in vitro glucose exposure on TNFα release from MNC of women with PCOS compared to those of ovulatory controls was examined.

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