Abstract
The activities of glucose 6-phosphate and 6-phosphogluconate dehydrogenase were measured in the lens and erythrocytes of man and several other species. There is a wide variation between individuals of the same species, but there seemed no correlation between the activity of either enzyme in the lens and their activity in the erythrocytes of the same species. There is a wide range of activity of both glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in the lens and in the blood of different species. Several species had glucose 6-phosphate dehydrogenase activity in erythrocytes below the level considered “deficient” in man. The sorbitol content of the lens was not correlated with glucose 6-phosphate dehydrogenase activity.
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