Abstract
Two hundreds and eighty one patients receiving sulfones (DDS, Protogen or Promin) or sulfamethoxypyridazine were examined by a Dichlorophenol indophenol (DPIP) test for Glucose-6-phosphate dehydrogenase (G6PD).The blood samples of 230 cases decolorized the dye within 80 minutes, while the residual 51 samples required 80 minutes or more. A quantitative UV test for G6PD were performed on 48 cases of these 51 patients.The result of the UV test showed that all of patients had G6PD values between 120 and 240 mU per 109 red blood cells except one male patient (114.4 mU). His red blood cells count and the hemoglobin index were within normal range and Heinz body in the red blood cells was negative though he was receiving 50 mg of DDS everyday.
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