Abstract
We studied the activities of glucose-6-phosphate dehydrogenase and catalase in erythrocytes of schizophrenia patients who were under pharmacotherapy with traditional antipsychotic drugs. Prior to therapy, we observed decreased activity of glucose-6-phosphate dehydrogenase and increased activity of catalase in patients compared to the control. After a 6-week therapy with antipsychotics of the first generation, catalase activity became normal, whereas the activity of glucose-6-phosphate dehydrogenase declined further.
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