Abstract
Abstract Liver biopsies from two patients with glucose-6-phosphatase deficiency were found to contain a high de novo fatty acid synthesizing activity from citrate as the carbon source. Liver biopsies from controls, from patients with debranching enzyme deficiency or from one patient with insulinoma showed much lower rates of long-chain fatty acid synthesis. From this investigation it is concluded that there is no correlation between fatty acid synthesis in the liver and the insulin and/or glucose levels in the blood. However, there may be a positive correlation between the activity of the rate-limiting step in long-chain fatty acid synthesis and the lactate level in the blood.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Clinica chimica acta; international journal of clinical chemistry
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
