Abstract
ABSTRACT Objective: We present a case of severe hypoglycemia in a patient with recurrent solitary fibrous tumor or non–islet cell tumor, maintained successfully in a euglycemic state with a combination of glucocorticoids and oral intake of uncooked cornstarch. Methods: Case report and literature review. Results: An 80-year-old Caucasian female with a history of solitary fibrous tumor of the lung treated with left lower lobectomy in 2009 had a recurrence in 2015 with a retroperitoneal tumor mass. She presented to our hospital with a syncopal episode and capillary blood glucose of 18 mg/dL. Routine laboratory studies were unrevealing. Fasting insulin-like growth factor 1 (IGF-1) was 228 ng/mL (normal range, 54 to 205 ng/mL), insulin-like growth factor 2 (IGF-2) was 541 ng/mL (normal range, 333 to 967 ng/mL), and the IGF-2:IGF-1 ratio was 2.3 (normal, <3.8). Large amounts of infused glucose barely maintained glycemia, and a trial of octreotide failed. Therefore, she was begun on uncooked cornstarch and predn...
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