Abstract
Six weeks of glucocorticoid treatment (triamcinolone-acetonide-21-phosphate, 1 mg/kg of body weight daily) resulted in a similar pattern of fibre type atrophy in jaw and hind-limb muscles. Fast-twitch glycolytic fibres were significantly atrophied in all muscles investigated. Fast-twitch oxidative glycolytic fibres were affected only in the fast (white) regions of the mixed muscles, while slow-twitch oxidative fibres were unaffected. The results from pair-fed controls (food intake matched to the glucocorticoid-treated animals) showed that the glucocorticoid produced an atrophic response in addition to that produced by the decreased food intake in the experimental animals. These results suggest that the jaw musculature shares the wasting effects induced by elevated circulating glucocorticoid levels often found in stress situations.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
