Abstract

In an adult exposed to trauma, the risk for post-traumatic stress disorder increases if the person had been abused as a child. Both child abuse and PTSD have been associated with dysregulation of cortisol and of the hypothalamic-pituitary-adrenal (HPA) axis. Single nucleotide polymorphisms (SNPs) in the FKBP5 gene (which modulates binding of glucocorticoid to its receptor) have been associated with peritraumatic dissociation in …

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