Abstract

Letters and Comments1 September 1970Glucagon and the Failing HeartPAUL D. WOOLF, M.D.PAUL D. WOOLF, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-73-3-493 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: The NIH Conference entitled "Adenyl Cyclase and Myocardial Contractility" (Ann Intern Med72:561-578, 1970) was most provocative. If one extrapolates from Dr. Epstein's findings of the glucagonmedicated increase in myocardial contractility and in myocardial adenyl cyclase in cats with acute cardiac decompensation, it would seem that glucagon might be useful in the somewhat analogous situation in man—that is, cardiogenic shock. However, since the evidence indicates that this hormone activates the same adenyl cyclase system as the catecholamines, it would appear from Dr. Levey's data that the use of either T3or T4or one of their analogues...Reference1. POOLSKELTONSEAGREN PCS: Chemical energetics of cardiac muscle in hyperthyroidism. J Clin Invest 47:80a, 1968 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Department of Medicine N.Y.U. School of Medicine New York, N.Y. 10016 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 September 1970Volume 73, Issue 3Page: 493-494KeywordsCatecholaminesGlucagonHeartHormonesShockTriiodothyronine Issue Published: 1 September 1970 PDF DownloadLoading ...

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