Abstract
Paraganglia have been divided [3619] into sympathogenic chromaffin and parasympathogenic nonchromaffin. The former derive from the adrenal medulla, the socalled free paraganglia, and some intraneural or intraganglionic chromaffin cells, from which chromaffin paragangliomas such as pheochromocytoma arise. The latter are represented by collections of epithelioid cells situated on the blood vessel wall in relation to the vagus and glossopharyngeal nerves. They go under the name of carotid, jugular, tympanic, vagal, aortic, and supracardiac paraganglia. Related tumors are glomus tumors or nonchromaffin paragangliomas or “chemodectomas” [2356]. An objection to the last nomenclature is that there has been no definitive demonstration of chemoreceptor function in these tumors [1095]; thus the term paraganglioma which may be specified as functioning or nonfunctioning, is preferable.
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