Abstract
In 80 patients with essential, mild to moderate, recent (<1 yr) hypertension, we examined the relationship between renal function, left ventricular mass, and diastolic filling. Glomerular filtration rate (GFR) was determined by 99Tc ml/min × 1.73 m 2; left ventricular mass and diastolic filling were determined by guided M-Mode echocardiography and by early-to-late mitral inflow velocity ratio (E/A), calculated by Doppler echocardiography. Results showed a significant increase of left ventricular mass index and E/A in hyperfiltrant patients. We concluded that a high GFR can be an indicator for early target organ damage in patients with recently diagnosed essential hypertension and normal renal function.
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