Globus-Based Grid Computing Simulations of Action Potential Propagation on Cardiac Tissues

Abstract

AbstractWith the advent of Grid technologies, the study of the electrical activity of the heart, by means of concurrent parametric simulations of the action potential propagation on cardiac tissues, can be greatly benefited. Studies of the electrical behaviour, such as late ischemia require the execution of multiple computational and memory intensive parametric simulations. This paper describes the integration, into a Grid infrastructure, of a parallel MPI-based system for the simulation of action potential propagation on a three-dimensional parallelepiped-modelled cardiac tissue. Developed upon the Globus Toolkit, it features state-of-the-art capabilities such as data compression, simulation failure recovery, and the combination of parallel execution on distributed resources, what has enabled an outstanding increase in research productivity.KeywordsGrid ComputingCardiac TissueParallel ExecutionAction Potential PropagationGrid InfrastructureThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.