Abstract

Globicatella sanguinis is a rare isolate in clinical samples. We present a case of meningitis in a 70-year-old male patient after a head injury operation. Three consecutive cerebrospinal fluid samples obtained from the patient identified Globicatella sanguinis based on morphology, biochemical profile, and Vitek-2 identification. The patient recovered after antibiotic treatment with vancomycin. This is the first case report of Globicatella sanguinis from Asia from a case of meningitis.

Highlights

  • Globicatella sanguinis is Gram-positive catalase negative coccus. It has been isolated from various human clinical specimens such as the blood of bacteremic patients, the urine of patients with urinary tract infections, cerebrospinal fluid of patients with meningitis, and wounds [1]

  • In the past Globicatella sanguinis was known as Streptococcus uberis because of the identification of viridans streptococci isolated in 1977 [4]

  • It was recognized as a new genus and species only after comparative 16S rRNA gene sequencing became available to gather new data for these strains [1]

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Summary

Introduction

Globicatella sanguinis is Gram-positive catalase negative coccus It has been isolated from various human clinical specimens such as the blood of bacteremic patients, the urine of patients with urinary tract infections, cerebrospinal fluid of patients with meningitis, and wounds [1]. The patient was started prophylactically on amoxicillin plus clavulinic acid and kept for observation in the intensive care unit for two days He underwent a right fronto-tempero-parietaloccipital [FTPO] decompressive craniectomy with evacuation of the hematoma and contusectomy. The patient was kept on a ventilator for two days and a tracheostomy was performed during the hospital course He was discharged fourteen days after admission, with left side hemiparesis, with a healing healthy wound at the surgical site on the scalp, and taking an oral diet. Nine days after discharge from hospital, the patient was readmitted with high-grade fever, heavy purulent discharge from the wound at the surgical site

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