Abstract
AimTo quantify and update the years of life lost (YLL), years lived with disability (YLD) and disability-adjusted life years (DALY) due to the adverse effects of medical treatment (AEMT) between 1990 and 2017.Subject and methodsWe analyzed the latest dataset from the Global Burden of Disease (GBD) 2017 study. We described the burden of AEMT based on the number of DALY. We additionally evaluated the global age and sex-specific DALY and compared the age-standardized rates of DALY across the World Health Organization (WHO) regions from 1990 to 2017.ResultsWorldwide, the total DALYs due to AEMT were 84.93 [95% uncertainty interval (UI), 62.52 to 102.21] in 1990 and 62.79 (52.09 to 75.45) in 2017 per 100,000 population. The global percentage of change in DALY showed a negative trend of −26.06 % (−41.52 to −10.59) across all WHO regions between 1990 and 2017. The YLD has increased during the period from 1997 to 2017 by 29.47% (17.87 to 41.06). In 2017, men were affected more than women with a DALY of 66.78 in comparison to 58.91 DALY in women. DALY rates per 100,000 were highest across all the WHO regions in the first years of life. The predicted DALY rates were 59.92 (57.52 to 62.32) in the year 2020, 50.36 (32.03 to 68.70) in 2030, and 40.8 (−1.33 to 82.93) in 2040.ConclusionUsing the GBD 2017 study data, we found a decrease in the DALY rate due to AEMT between 1990 and 2017 with a varying range of DALY between different WHO regions. DALY also differed by age and sex. The forecasting analyses showed a decrease in DALY due to AEMTs with a significant drop in the European region when compared to the African and American regions. However, the increasing trend for YLD signifies an increasing burden of people living with poor health due to AEMT. Our study proposes to identify disability due to AEMT as a significant public health crisis and calls for policymakers to create a robust revised policy.
Highlights
In 2000, the Institute of Medicine released a groundbreaking report estimating that between 44,000 and 98,000 people die annually in US hospitals because of medical errors [1]
Using the Global Burden of Disease (GBD) 2017 study data, we found a decrease in the disability-adjusted life years (DALY) rate due to adverse effects of medical treatment (AEMT) between 1990 and 2017 with a varying range of DALY between different World Health Organization (WHO) regions
The increasing trend for years lived with disability (YLD) signifies an increasing burden of people living with poor health due to AEMT
Summary
The amount of data collection regarding medical errors has increased dramatically, allowing us to assess mortality from medical errors and the rates of morbidity Such AEMTs present as both a significant economic and a social burden. Some of those who survive medical errors may still suffer significant harm leading to disability, which, in turn, affects the quality of life and incurs the costs of continuing medical care and lost productivity. AEMT is a substantial burden on society and on the person affected with loss of health that is measured in disability-adjusted life years (DALY) [7] Evaluating both morbidity and mortality provides a more accurate picture of both the incidence as well as the burden of AEMT [8]
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