Global, regional, and national incidence and mortality of human monkeypox infection in 107 countries and territories, October 2022: a systematic analysis for World Health Organization database and rapid review

Abstract

The monkeypox is an unusual viral disease which, until recently, has rarely been detected outside of Africa. Approximately over 70,000 laboratory-verified or suspected cases of human monkeypox have been discovered in at least 107 countries in a matter of months. A total of 71,237 laboratory confirmed cases, 1,097 probable cases, and 26 related deaths regarding the monkeypox were confirmed worldwide up to October 6th, 2022. Among the six World Health Organization regions, the Americas demonstrated the highest total laboratory-confirmed monkeypox cases (45,342 cases), followed by the European Region (24,889 cases), the African Region (727 cases), the Western Pacific Region (189 cases), the Eastern Mediterranean Region (67 cases), and the South-East Asia Region (23 cases). The nation with the highest cumulative monkeypox cases was the United States of America (26,723 cases), followed by Brazil (8,147 cases), Spain (7,209 cases), France (4,043 cases), The United Kingdom (3,654 cases), and Germany (3,640 cases). This international and comprehensive review, through analysis of the types and differences among the virus, the reason of its epidemic, and current available vaccines, aims to provide crucial information needed for monkeypox research and enhance global health policies in an individual- and country-level strategies towards the treatment of monkeypox.