Global Patterns of Lung Cancer Incidence

Abstract

Introduction It is well known that smoking is injurious to health which causes lung cancer. Although not all smokers develop lung cancer, fraction of lifelong non-smokers will die from lung cancer. Lung cancer is a major cause of cancer related death in developed countries with extremely poor overall survival rate. In present study we set out epidemiological pattern with clinical profile of lung cancer patients in northern india population. Aim:We evaluate the effect of smoking with age distribution on histopathology in lung cancer patients. Material & Methods: We enrolled 218 patients after confirmation of histopathology and also collected demographic data. Results: Out of 218 patients of lung cancer, having median age of 56 years, we found 149 (68.3%) were smokers and 69 (31.6%) were nonsmokers. In histopathology 54.1% patients had squamous cell carcinoma, 29.2% adenocarcinoma, 12.4% Mixed cell, 3.7% Small cell. We also found 63.1% smoker to have squamous cell carcinoma and 50.7% non-smoker have adenocarcinoma.In our study middle age group patients were more frequent in smoking group. While higher age group patients has squamous cell and middle group have adenocarcinoma. Therefore patients group with high smoking are found to develop have more risk to develop small cell carcinoma rather than in case of non-smoker higher age groups have sqamous cell carcinoma type. Conclusion: In this study we found middle age group subjects of smoker having more squamous cell and nonsmoker having adenocarcinoma.