Abstract
Global pattern and trend of liver cancer survival: a systematic review of population-based studies
Highlights
Primary liver cancer (PLC) is the sixth most common cancer and the fourth most common cause of cancer death worldwide[1]
The greatest difference in overall 5-year relative survival rate (RSR) between male and female was observed in Scotland during 2005-2007 (4.4% for male and 10.6% for female)[18], followed by the USA during 1986-1988 (3.5% for male and 8.5% for female)[14]
In age-standardized 5-year RSRs, the greatest difference was observed in Norway during 1990-1994 and 19941998[24]
Summary
Primary liver cancer (PLC) is the sixth most common cancer and the fourth most common cause of cancer death worldwide[1]. The top five countries with the highest incidence of liver cancer are Mongolia (71.8/100,000), Thailand (33.7/100,000), North Korea (32.3/100,000), Japan (27.9/100,000), and China (27.6/100,000)[2]. According to Global cancer statistics 2018[1], an estimated 841,080 incident cases of liver cancer occurred worldwide, with 392,868 in China, accounting for 46.71%. It is crucial to comprehend and employ survival rate, which is another important descriptive indicator of disease burden and widely used in the evaluation of cancer prognosis. Survival data are available from three sources: clinical studies, hospital-based follow-up data, and population-based followup data[4]. Population-based survival data usually exclude death certificate only (DCO) and autopsy cases during analysis because evidence of diagnosis is weak
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