Abstract
BackgroundKnee osteoarthritis (KOA) is a prevalent form of chronic joint disease associated with functional restrictions and pain. Activity limitations negatively impact social connectedness and psychological well-being, reducing the quality of life (QoL) of patients. The purpose of this review is to summarize the existing information on QoL in KOA patients and share the reported individual factors, which may influence it.MethodsWe conducted a systematic review examining the literature up to JAN/2017 available at MEDLINE, EMBASE, Cochrane, and PsycINFO using KOA and QOL related keywords. Inclusion criteria were QOL compared to at least one demographic factor (e.g., age, gender), lifestyle factor (e.g., functional independence), or comorbidity factor (e.g., diabetes, obesity) and a control group. Analytical methods were not considered as part of the original design.ResultsA total of 610 articles were reviewed, of which 62 met inclusion criteria. Instruments used to measure QoL included: SF-36, EQ-5D, KOOS, WHOQOL, HAS, AIMS, NHP and JKOM. All studies reported worse QoL in KOA patients when compared to a control group. When females were compared to males, females reported worse QOL. Obesity as well as lower level of physical activity were reported with lower QoL scores. Knee self-management programs delivered by healthcare professionals improved QoL in patients with KOA. Educational level and higher total mindfulness were reported to improve QoL whereas poverty, psychological distress, depression and lacking familial relationships reduce it. Surgical KOA interventions resulted in good to excellent outcomes generally; although, results varied by age, weight, and depression.ConclusionKOA has a substantial impact on QoL. In KOA patients, QoL is also influenced by specific individual factors including gender, body weight, physical activity, mental health, and education. Importantly, education and management programs designed to support KOA patients report improved QoL. QoL data is a valuable tool providing health care professionals with a better comprehension of KOA disease to aid implementation of the most effective management plan.
Highlights
Knee osteoarthritis (KOA) is a prevalent form of chronic joint disease associated with functional restrictions and pain
The goal of treatment has traditionally focused on reducing pain and improving function, yet healthcare providers are increasingly realizing the importance of ensuring implementation of psychosocial support to improve the health and overall well-being of KOA patients
As far as we know, this is the first systematic review summarizing existing studies results reporting quality of life (QoL) in KOA patients combined with individual factors such as demographics, lifestyle, or comorbidities
Summary
Knee osteoarthritis (KOA) is a prevalent form of chronic joint disease associated with functional restrictions and pain. Activity limitations negatively impact social connectedness and psychological well-being, reducing the quality of life (QoL) of patients. The purpose of this review is to summarize the existing information on QoL in KOA patients and share the reported individual factors, which may influence it. In addition to the structural and functional limitations caused by KOA, pain and disability from KOA affect social connectedness, relationships and emotional well-being; subsequently, reducing quality of life (QoL) [4]. As far as we know, this is the first systematic review summarizing existing studies results reporting QoL in KOA patients combined with individual factors such as demographics (e.g., age, gender), lifestyle (e.g., functional independence), or comorbidities (e.g., diabetes, obesity)
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