Abstract
The global agenda for malaria has, once again, embraced the possibility of eradication. As history has shown, there will be no single magic bullet that can be applied to every epidemiological setting. Africa has a diverse malaria ecology, lending itself to some of the highest disease burden areas of the world and a wide range of clinical epidemiological patterns making control with our current tools challenging. This commentary highlights why the epidemiology of Plasmodium falciparum malaria in Africa should not be forgotten when planning an eradication strategy, and why forgetting Africa will, once again, be the single largest threat to any hope for global eradication.
Highlights
Malaria is a mosquito borne disease which, in humans, is caused by five protozoa: Plasmodium falciparum, P. vivax, P. malariae, related sibling species of P. ovale, and P. knowlesi
After a decade of Roll Back Malaria in Africa, almost 184 million Africans still live under conditions of hyperholoendemic transmission [12], despite impressive coverage of insecticide-treated nets (ITNs) since 2006
As we pursue an agenda to shrink the world malaria map, Africa remains the focus of greatest disease burden and cannot be forgotten
Summary
Malaria is a mosquito borne disease which, in humans, is caused by five protozoa: Plasmodium falciparum, P. vivax, P. malariae, related sibling species of P. ovale, and P. knowlesi. P. falciparum remains the single most important threat to public health at a global scale, accounting for more than 90% of the world’s malaria mortality.
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