Abstract
BackgroundStatistical data on the incidence, mortality, and burden of breast cancer and the relevant risk factors are valuable for policy-making. We aimed to estimate breast cancer incidence, deaths, and disability-adjusted life years (DALYs) by country, gender, age group, and social-demographic status between 1990 and 2017.MethodsWe extracted breast cancer data from the 2017 Global Burden of Disease (GBD) study from 1990 through 2017 in 195 countries and territories. Data about the number of breast cancer incident cases, deaths, DALYs, and the age-standardized rates were collected. We also estimated the risk factors attributable to breast cancer deaths and DALYs using the comparative risk assessment framework of the GBD study.ResultsIn 2017, the global incidence of breast cancer increased to 1,960,681 cases. The high social-development index (SDI) quintile included the highest number of breast cancer death cases. Between 2007 and 2017, the ASDR of breast cancer declined globally, especially in high SDI and high middle SDI countries. The related DALYs were 17,708,600 in 2017 with high middle SDI quintile as the highest contributor. Of the deaths and DALYs, alcohol use was the greatest contributor in most GBD regions and other contributors included high body mass index (BMI) and high fasting plasma glucose.ConclusionThe increasing global breast cancer burden is mainly observed in lower SDI countries; in higher SDI countries, the breast cancer burden tends to be relieving. Therefore, steps against attributable risk factors should be taken to reduce breast cancer burden in lower SDI countries.
Highlights
Statistical data on the incidence, mortality, and burden of breast cancer and the relevant risk factors are valuable for policy-making
The aim of this study was to describe the influence of geographical location, social-development index (SDI), age, and gender on the global trends in the incident cases, deaths, and Disability-adjusted life year (DALY) of breast cancer based on data from the Global Burden of Disease from 1990 to 2017 in 195 countries and territories
Breast cancer incidence burden Globally, the incident cases of breast cancer has increased to 1,960,681(95% Uncertainty interval (UI) = 1,891,447–2,023,170) with an Age-standardized incidence rate (ASIR) of 24.19/100,000 persons (95% UI = 23.34–24.86) in 2017 (Table 1)
Summary
Statistical data on the incidence, mortality, and burden of breast cancer and the relevant risk factors are valuable for policy-making. We aimed to estimate breast cancer incidence, deaths, and disability-adjusted life years (DALYs) by country, gender, age group, and social-demographic status between 1990 and 2017. Several regional and national studies on breast cancer incidence and mortality have been performed, and the results of these multifarious studies from different parts of the world present an inclusive picture. Specific studies of breast cancer burden at a global level are lacking. The aim of this study was to describe the influence of geographical location, social-development index (SDI), age, and gender on the global trends in the incident cases, deaths, and DALYs of breast cancer based on data from the Global Burden of Disease from 1990 to 2017 in 195 countries and territories
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