Abstract

Central nervous system (CNS) tumours are the most common solid neoplasms of childhood and account for 20% of all malignancies in this age group. Gliomas constitute 40–60% of all childhood primary brain tumours[ 1 Young Jr, J.L. Miller R.W. Incidence of malignant tumors in US children. J Pediatr. 1975; 86: 254-258 Abstract Full Text PDF PubMed Scopus (756) Google Scholar ]. Low-grade astrocytomas are the most common neoplasms of childhood glial tumours[ 2 Cohen ME, Duffner PK. Brain Tumors in Children. New York, Raven Press 1994. Google Scholar ]. Astrocytomas are seen more frequently in the supratentorial compartment, although the cerebellar hemispheres are also a common site for astrocytoma[ 3 Packer R.J. Vezina G. Pediatric glial neoplasms including brain-stem gliomas. Seminars Oncol. 1994; 21: 260-272 PubMed Google Scholar ]. High-grade gliomas also predominantly arise in the supratentorial compartment, although brainstem gliomas are common malignancies arising in the infratentorial compartment. In this review we will discuss all histological types of paediatric gliomas including the different anatomical locations, treatment options and prognoses.

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