Glioma pontino intrínseco difuso : paralelo entre el niño y el adulto.

Abstract

Brainstem tumors account for 10-20% of pediatric brain tumors, diffuse intrinsic pontine glioma is the most common brainstem tumor of childhood. Diffuse intrinsic pontine glioma is a heterogeneous group of tumors that are biologically distinct from other pediatric and adult high grade gliomas. Patients with diffuse intrinsic pontine gliomas have a rapid cranial nerve deficit, paresis or ataxia, the appearance of these lesions on nuclear magnetic resonance is characteristic. Diffuse intrinsic pontine glioma is a therapeutic challenge in neurooncology. Chemotherapy has not proven to be a treatment that stops or slows tumor growth. Radiation therapy is the only valid treatment, but its efficiency is only transient. This article describes two clinical cases involving a pediatric and adult patient, diagnosed with diffuse intrinsic pontine glioma, the purpose is to do a parallel between the cases.