Glioblastoma, Treatment Strategies at the "Hermanos Ameijeiras" Hospital.

Abstract

Objective: Gliomas are the most common primary malignant tumors of the central nervous system (CNS) and, from them, 45.6 % corresponds to glioblastomas (GB). This work aims to determine the results of treatment for patients with glioblastomas treated at the “Hermanos Ameijeiras” Hospital, Cuba, in the period from January 2015 to December 2020. Method: An observational, descriptive, retrospective cohort assessment was carried out in a population of 45 patients treated at the “Hermanos Ameijeiras” Hospital, Cuba, with a diagnosis of glioblastoma. Results: Male patients aged 40 to 59 years (57.7 %) with white color skin (82 %) were predominant with clinical symptoms of motor deficit syndrome. The survival rate was greater than 12 months in 18 patients (40 %), while for 21 patients (46.7 %) it was between 6 and 12 months. Conclusions: Glioblastoma is a challenge for the multidisciplinary medical team. The best therapeutic results and survival rates are related to the strategies of a multimodal treatment that begins with maximum safe resection of the lesion, followed by radiotherapy, chemotherapy and immunotherapy oncological treatments.