Glioblastoma in an old patient treated with a combination of tumor-treating fields and standard chemoradiotherapy: A case report

Abstract

Glioblastoma (GBM) is the most common type of primary brain tumor in adults. Due to the lack of clinical data, there is no standard treatment for GBM in old patients, and the prognosis is poor. We report a case of a 69-year-old female patient diagnosed with GBM who received tumor resection, radiotherapy, and temozolomide combined with tumor-treating fields (TTFields), and the overall survival (OS) of this patient was 13 months. The addition of TTFields to standard chemoradiotherapy may prolong the OS and not exacerbate toxicities in the treatment of old GBM patients. This provides more treatment options for old GBM patients. The study was approved by the Ethics Committee of The First Affiliated Hospital of Soochow University, China (No. 499/2023) on November 28, 2023.