Abstract
Reactions of the glia and blood vessels in the sensomotor cortex of adult rats to intraperitoneal injection of angiotensin II were studied electron-microscopically. Repeated injections of the hormone led to edema of increasing severity of the astrocytes, constriction of the lumen of the capillaries, and changes in the structure of their endothelium. It is suggested that these disturbances may be the cause of the cerebrovascular insufficiency and of functional changes in the CNS.
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