Glial heterotopia presenting as nasal polyp - Report of two cases

Bhawna Bhutoria,Manish Nigam,Soma Datta,Uma Banerjee

doi:10.3329/bjms.v12i1.13360

Abstract

This report described two cases of nasal glial heterotopia which primarily presented as nasal polyp. Glial heterotopia one form of congenital midline nasal mass is a rare anomaly usually detected at birth. There are congenital malformation of displaced normal, mature glial tissue, which is no longer in continuity with an intracranial component. The case reports correlates clinical findings with immunohistochemical investigations. DOI: http://dx.doi.org/10.3329/bjms.v12i1.13360 Bangladesh Journal of Medical Science Vol. 12 No. 01 January13 pp.104-107

Highlights

Nasal glial heterotopia is considered to be congenital malformation of displaced normal, mature glial tissue, which is no longer in continuity with an intracranial component[1]
Glial Heterotopia, one of the congenital midline nasal mass is a rare anomaly usually detected at birth
Nasal glial heterotopia is a specific type of choristoma

Summary

Introduction

Nasal glial heterotopia is considered to be congenital malformation of displaced normal, mature glial tissue, which is no longer in continuity with an intracranial component[1] This is distinctly different from an encephalocle, which is a herniation of brain tissue and/or leptomeninges, that develops through a defect in the skull, where there is continuity with the cranial cavity[1]. If there is a concurrent cerebrospinal fluid (CSF) leak, an encephalocele is much more likely[3] They are categorised into two types based on the anatomic site of presentation:Extranasal (60%) located in subcutaneous bridge of nose;Intranasal (30%) located in superior nasal cavity and mixed (10%) located in subcutaneous tissues and nasal cavity which are larger in size[1,2,3]. IV, V: Expression of S 100 protein in glial heterotopic tissue (Immunoperoxidase- antiperoxidase staining , 100x)

Discussion

Findings

Conclusion