Abstract
AbstractA simple, rapid GLC method for the determination of therapeutic levels of lidocaine in plasma or blood is described. After extraction with benzene from alkalinized plasma, the compound is analyzed by GLC using a nitrogen-sensitive detector. Quantitation is accomplished using an internal standard and a standard curve, which was linear over the 0.1–10-μg range. The limit of detection was approximately 10 ng/ml. Recovery of the parent compound was essentially quantitative. Plasma data are presented to demonstrate the utility of the method.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
