Abstract

In 1957, Eisenman and associates demonstrated that certain sodium aluminum silicate glasses had a high affinity for sodium and potassium ions and could be used for the measurement of these ions in solutions. Moore and Wilson and Friedman and associates have demonstrated that these sodium and potassium selective glasses can be used for the determination of sodium and potassium in various body fluids, including blood. With some recent improvements in electrode construction, we have made simple capillary electrodes capable of measuring sodium and potassium in small samples of whole blood, plasma, serum, or cerebrospinal fluid.' This paper presents a comparison of the glass electrode and flame photometer methods for determining the sodium and potassium content of whole blood, plasma, and serum. Comparison is made between whole blood and plasma at body and at room temperature, and between plasma and serum.

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