Abstract

Introduction: Glandular odontogenic cyst (GOc) is uncommon jaw cyst of odontogenic origin with unpredictable and potentially aggressive behavior. It is a rare developmental cyst with relatively low frequency of just 0.012–0.03%. Very limited cases of GOc have been reported in literature since it was first described by Gardner et al. in 1988. GOc is found to occur in fifth decade of life and the most common site of occurrence is mandible, especially the mandibular anterior region with slight predilection for males. However, its occurrence in the maxillary posterior region of a 23-year-old female with associated symptoms of pain is quite rare. case report: this case report presents one such rare case of GOc in right maxillary region of a 23-year-old female who was primarily diagnosed as a radicular cyst. Later, due to recurrence of the lesion, patient had to undergo enucleation and partial resection of posterior maxilla, and after a comprehensive histopathological analysis, it

Highlights

  • Glandular odontogenic cyst (GOC) is uncommon jaw cyst of odontogenic origin with unpredictable and potentially aggressive behavior

  • Case Report: This case report presents one such rare case of GOC in right maxillary region of a 23-year-old female who was primarily diagnosed as a radicular cyst

  • In conclusion, Glandular odontogenic cyst being such a rare entity, this paper may enhance the existing knowledge about GOC and may guide readers and clinicians to pay special attention to similar cases when encountered in clinical work

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Summary

INTRODUCTION

Glandular odontogenic cyst (GOC) is a rare developmental cyst of odontogenic origin. Padayachee and Van Wyk initially reported it as a sialo odontogenic cyst in 1987 [1] but its odontogenic origin was first described by Gardner et al in 1988 who proposed the name ‘GOC’ [2]. GOC is characterized by a non-keratinized stratified squamous epithelial lining with papillary projections, focal plaque like thickenings within the lining, microcysts or intraepithelial crypts containing mucin, ‘mucous lakes’ and hyaline bodies It includes cuboidal basal cells, sometimes vacuolated and absence of inflammation in the subepithelial connective tissue [12, 13]. In order to further elucidate the nature of the lesion and to provide final diagnosis, we carried out an incisional biopsy and a part of cystic lining was excised through the perforations of cortical bone and the specimen was subjected to histopathological and immunohistochemical examination. Histopathological and immunohistochemical examination findings were indicative of ‘glandular odontogenic cyst’ a final diagnosis of GOC was Figure 4: (A, B) Photomicrograph of the initial specimen showing non-keratinized stratified squamous epithelial lining of varying thickness with epithelial hyperplasia. One year follow-up showed improved bone healing with no signs of relapse

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