Giresun ilindeki 106 Behçet hastasının retrospektif değerlendirilmesi

Abstract

Background Behçet’s disease (BD) is a multisystem inflammatory disorder which is an important cause of morbidity in Turkey.Objective We aimed to investigate the demographical and clinical features of patients with BD followed up in our department in Faculty of Medicine in Giresun University Training and Research Hospital.Methods The hospital records of patients with BD who attended the dermatology department between 2006-2019 were retrospectively evaluated. One hundred and six patients who met the diagnostic criteria of International Study Group for BD were included in the study. The clinical and demographic characteristics, including the age of onset, disease duration, mucocutaneous findings and systemic involvements were recorded.Results Of the 106 patients in the study, 64 (60.4%) were female, 42 (39.6%) were male, and the female-to-male ratio was 1.52:1. The median age at the onset of the disease was 38 years, and the median disease duration was 9 years (range 1-40 years). The most common finding was recurrent oral ulcers (100%) followed by genital ulcers (86.6%), ocular involvement (52.8%), erythema nodosum (49.1%), articular involvement (45.3%), papulopustular lesions (34%), positive pathergy test (21.7%), vascular involvement (14.2%), gastrointestinal involvement (9.4%), neurologic (2.8%) and genitourinary involvement (2.8%). Papulopustular lesions were seen statistically significantly more frequent in men (P=0.047).Conclusion In our study, we presented the demographical and clinical features of patients with BD in a single center in Giresun. Major findings were mucocutaneous ones and most common extracutaneous involvements were eyes and joints.