Ginsenosides: An overview of its antiplatelet effects and its underlying mechanisms

Abstract

GINSENOSIDES, the principal constituent of plants from genus Panax, have been indicated in multitudinous of ailments by the Homos sapiens, for more than 2 millennia. Mostly and notably the ginsenosides, the mainstay of Chinese herbal system of medication, are harnessed for multifarious disorders viz. Neurodegenerative diseases, Diabetes mellitus, Cardiovascular abnormalities, Septic shock, inflammatory disorders, Obesity and most striking of all owing to the prevalent circumstances have to potential to manage, even treat COVID-19, albeit empirically. Whereas, considering the plant itself, it strikes to the researcher as perennial although, with significantly slow progress. The spectrum of the review encompasses the functional reach of the ginsenosides with special emphasis on the antiplatelet therapeutics, in conjunction with the notoriety and the prospect of the compounds in multitude of disorders. However, the mechanism on which the edifice, of the antithrombotic efficiency is contingent, is expressed with keen interest. Ultimately, the root or its extract, is evidenced to be sufficiently effective in curbing the foresaid ailments whether authenticated by systematic review, clinical trials, mechanistic patterns and animal investigations. Overall, the herb shows immense potential to be packaged into a unit dosage form and be brought in the prevalent market especially as an antithrombotic agent.