Abstract
Some terpenoids play important roles in plant development as growth regulators. Gibberellins (GAs) are a group of diterpenoids, of which isoprene units are mainly derived from the methylerythritol phosphate pathway in the plastid. Geranylgeranyl diphosphate, a common precursor for diterpenoids, is converted to biologically active GAs through reactions catalyzed by terpene cyclases, cytochrome P450 monooxygenases, and 2-oxoglutarate-dependent dioxygenases. Bioactive GAs act as critical growth regulators throughout the life cycle of plants. There is accumulating evidence that the cellular concentration of hormonal GAs is strictly regulated by multiple endogenous and environmental cues. This review aims to summarize our recent findings on the regulation of GA biosynthesis in the model species Arabidopsis thaliana, with emphasis on the use of the genome information, transcriptome analysis and relevant mutants.
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