Abstract
Aim:Giardia is a serious zoonotic parasite, which causes diarrheal disease in humans and animals including rodents. The purpose of this study was to estimate the prevalence of Giardia spp. in brown rats (Rattus norvegicus) in Grenada.Materials and Methods:Intestinal contents from 99 and serum samples from 169 brown rats (R. norvegicus) from Grenada were collected. These samples were examined for the Giardia coproantigens using Cryptosporidium/Giardia Quik Chek assay (Tech lab® Inc., USA), and the serum was screened through an enzyme-linked immunosorbent assay (ELISA) test kit for Giardia antibody (anti-GD) ELISA kit (MyBioSource, San Diego, CA, USA).Result:Giardia coproantigens were positive in 17.17% (95% confidence interval [CI]; 10.33-26.06%) rats, whereas 55% (95% CI: 47.20-62.68) were positive with serum antibodies (anti-GD) to Giardia.Conclusion:The prevalence of Giardia spp. in brown rats in Grenada was moderate based on the presence of coproantigens in the intestinal contents and antibody in serum. The findings of Giardia infections and prevalence in brown rats will help veterinarians and physicians to better plan diagnostic and preventative strategies. This is the first report of prevalence of Giardia in brown rats in Grenada.
Highlights
Giardia spp. is a flagellate unicellular protozoan causing disease in humans and animals
Materials and Methods: Intestinal contents from 99 and serum samples from 169 brown rats (R. norvegicus) from Grenada were collected. These samples were examined for the Giardia coproantigens using Cryptosporidium/Giardia Quik Chek assay (Tech lab® Inc., USA), and the serum was screened through an enzyme-linked immunosorbent assay (ELISA) test kit for Giardia antibody ELISA kit (MyBioSource, San Diego, CA, USA)
The prevalence of Giardia spp. in brown rats in Grenada was moderate based on the presence of coproantigens in the intestinal contents and antibody in serum
Summary
Giardia spp. is a flagellate unicellular protozoan causing disease in humans and animals. A wide range of animals including rodents is believed to be a reservoir of G. lamblia [3,4]. This flagellated protozoan parasite has a direct life cycle. Cysts of Giardia spp. are voided in feces from infected host and contaminate food, water, and the environment. Transmission to a new host is through ingestion of food and water contaminated with Giardia cysts or direct transmission through ingestion of cysts from person-to-person or animal-to-person
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