Giant squamous cell carcinoma in a patient with epidermodysplasia verruciformis

Abstract

Epidermodysplasia verruciformis is an autosomal recessive skin disease usually presenting as multiple flat warts and pityriasis versicolor-like macules in early youth, possessing a great risk of developing skin cancer due to a lack of defense against beta HPV. Herein, we report the case of a 29-year-old female, a known case of EV, who presented with a verrucous growth on the forehead persistent for the previous one year. While clinical and dermoscopic examinations led to the suspicion of squamous cell carcinoma, it was confirmed by histopathological examination following a skin biopsy. Key words: Epidermodysplasia verruciformis; SCC; Dermoscopy