Abstract

Giant Sebaceous Cell Carcinoma of Upper Eyelid - Case Report

Highlights

  • A diagnosis of sebaceous cell carcinoma was confirmed on histopathology

  • Sebaceous gland carcinomas are highly malignant lid tumors which originate from meibomian glands and rarely from gland of Zeis, sebaceous gland of caruncle, eyebrows and periocular skin [1]

  • Histopathology report showed poorly differentiated sebaceous cell carcinoma with circumferential margins involved by the tumor (Figure 3c, Figure 3d, Figure 3e and Figure 3f)

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Summary

Introduction

Sebaceous gland carcinomas are highly malignant lid tumors which originate from meibomian glands and rarely from gland of Zeis, sebaceous gland of caruncle, eyebrows and periocular skin [1]. Eyelid Sebaceous gland carcinoma is an aggressive tumor causing metastasis related mortality in 3-41% [3,4,5,6,7,8,9,10]. An eighty-year-old male presented to us with mass right eye upper lid for past 2 years. A right upper eyelid swelling of 50 mm × 57 mm involving lid margin with ulceration with areas of necrosis and bleeding points. Contrast enhanced computed tomography (CECT) (Figure 2) showed large heterogeneously enhancing exophytic soft tissue density mass lesion with few hyperdense foci noted involving skin and subcutaneous tissue of upper right eyelid measuring approx. Histopathology report showed poorly differentiated sebaceous cell carcinoma with circumferential margins involved by the tumor (Figure 3c, Figure 3d, Figure 3e and Figure 3f). On first post-operative (Figure 4a) day a temporary temporal tarsorraphy was done and the patient was discharged and follow up done on 1 week (Figure 4b)

Discussion
Conclusion

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