Abstract
BackgroundDue to its rarity, little is known about the clinical presentations and responses to systemic chemotherapies in advanced and/or metastatic cases of paratesticular liposarcoma.Case presentationHere, we report the case of a 75-year-old Japanese man with giant paratesticular liposarcoma. Imaging studies revealed a 26 cm tumor in his right scrotum and lung metastases at presentation. He underwent radical orchiectomy followed by systemic chemotherapies. Pathological findings of the resected primary tumor confirmed a dedifferentiated liposarcoma. He then started chemotherapy treatment with gemcitabine plus docetaxel. His disease status was stable for 1 year. Eribulin was used for second-line chemotherapy. He had a relapse at 5 months after eliburin and died at 22 months after diagnosis.ConclusionEarly diagnosis and curative radical surgery are important for treatment of paratesticular liposarcoma. However, a giant paratesticular liposarcoma could cause metastases, and systemic chemotherapy may be helpful for prolonging survival in patients with metastatic paratesticular liposarcoma.
Highlights
ConclusionDiagnosis and curative radical surgery are important for treatment of paratesticular liposarcoma
Due to its rarity, little is known about the clinical presentations and responses to systemic chemotherapies in advanced and/or metastatic cases of paratesticular liposarcoma.Case presentation: Here, we report the case of a 75-year-old Japanese man with giant paratesticular liposarcoma
Early diagnosis and curative radical surgery are important for treatment of paratesticular liposarcoma
Summary
We described a case of giant paratesticular liposarcoma initially presenting with pulmonary metastases, along with the treatment outcome. Systemic chemotherapy may be helpful for prolonging survival, further studies regarding therapeutic strategies for inoperable and metastatic paratesticular liposarcomas are warranted
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