Abstract
Giant mitochondria (megamitochondria) measuring up to 14 µm in length and 3 µm in width are sporadically present in an exclusively interfibrillar position in the cardiomyocytes of a patient with restrictive cardiomyopathy. The number of cristae is augmented in the megamitochondria; these internal membranes are for the most part irregularly arrayed, but in certain giant mitochondria they run a parallel, zigzag course imparting a paracrystalline appearance to such organelles. Many of the giant mitochondria have one or several lucent, single membrane-bound inclusions that contain either f - or g -glycogen particles. Megamitochondria probably originate at least in part by fusion of adjacent organelles.
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