Abstract
Giant cerebral tuberculoma is an uncommon but serious form of tuberculosis. We report two patients who had a single, large lesion on magnetic resonance imaging (MRI) of the brain. Both patients underwent neurosurgery for the excision of the mass lesion as neuroimaging findings were suggestive of a brain tumor. Tuberculoma was later diagnosed on histopathological examination. We want to highlight that cerebral tuberculomas can mimic malignant brain tumors, as the clinical, laboratory, and radiologic features of cerebral tuberculomas are nonspecific.
Highlights
Tuberculosis of the central nervous system is less common compared with other organ systems [1]
We report two patients who had a single, large lesion on magnetic resonance imaging (MRI) of the brain
We present two patients who had a giant cerebral tuberculoma that mimicked a malignant brain tumor on magnetic resonance imaging (MRI)
Summary
Tuberculosis of the central nervous system is less common compared with other organ systems [1]. We present two patients who had a giant cerebral tuberculoma that mimicked a malignant brain tumor on magnetic resonance imaging (MRI). Both the patients underwent craniotomy and excision of the intracranial mass, which was later diagnosed as tuberculoma on histopathological examination. A 26-year-old man presented to the hospital with a one-month history of progressive intermittent headache, which was associated with dizziness and vomiting. He had swaying of the body to the left while walking. The histopathologic examination found a granulomatous inflammatory lesion consistent with the diagnosis of a tuberculoma. ATT was started and continued for 18 months with complete clinical and radiologic recovery
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