Giant Cell Tumor with Multi-Focal Pulmonary, Scapular and Rib Metastases in A 65-Year Old Hypertensive Woman

Anas Ismail,Kabiru Isyaku,Adekunle Y Abdulkadir

doi:10.15197/sabad.1.11.33

Abstract

Giant cell tumors is a primary benign bone tumors but with a tendency for significant local bone destruction, recurrence, and occasionally, distant metastasis. Most metastases are to the lungs but rarely metastases to the regional lymph nodes, the scalp, and the pelvis have been reported. Giant cell tumor in the elderly are very rare; and to the best of our knowledge, there is no prior report on concomitant pulmonary, scapular and rib metastases from giant cell tumor in the elderly in the literature at the moment. Hence, a case in a 65-year-old woman is presented.

Highlights

Giant cell tumors (GCTs) constitute about 5% of all bone tumors and about 21.5% of all primary benign bone tumors; with slight female predominance [1,2,3,4]
The peak age incidence of GCT is the third decade of life, with slight female prepondenrance [2,6] the presented case is female but was seen in the seventh decade
An important differential of GCT is osteoclastoma of hyperparathyroidism, [7] which in this case, was excluded by normal renal function test, serum levels of calcium, phosphate and alkaline phosphatase

Summary

INTRODUCTION

Giant cell tumors (GCTs) constitute about 5% of all bone tumors and about 21.5% of all primary benign bone tumors; with slight female predominance (female-tomale ratio of 1.40:1.28) [1,2,3,4]. Received: 27.04.2012, Accepted: 26.12.2012 are very rare; and to the best of the knowledge of this author, there is no prior report on concomitant pulmonary, scapular and rib metastases from GCT in the elderly in the literature at the moment. A case in a 65-year-old woman is presented. A sixty five-year-old woman was referred to the medical outpatient clinic of Aminu Kano teaching hospital on account of two-month history of cough, difficulty with breathing and swelling on the right shoulder region. There was no history of orthopnea, paroxysmal nocturnal dyspnea or fever. She had a bone curettage and grafting of giant cell tumor of the proximal right tibia five years prior to presentation, which was incidentally diagnosed following one year history of knee

Giant cell tumor

Findings

DISCUSSION