Abstract

The synovial membrane lines our joints, tendons, and bursae. This layer of specialized cells can change shape depending on the surrounding anatomical location (Goldblum, Weiss, & Folpe, 2014); perhaps this adaptability is what prompted early investigations of tumors that can arise in these locations (Jaffe, Lichtenstein, & Sutro, 1941). The most common group of tumors that develop from the synovial membrane (i.e., tenosynovial giant cell tumors) are classified as localized or diffuse based on their growth pattern and location (de St. Aubain Somerhausen & van de Rijn, 2013; Goldblum et al., 2014).

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