Giant cell tumor of soft tissue on the thigh of a 40-year-old woman

Abstract

We report a case of giant cell tumor of soft tissue (GCTST) in a 40-year-old woman who presented with a painful fibrous nodule on the thigh. The histological examination revealed multinucleated histiocytes admixed with eosinophils, lymphocytes, and scattered spindle-shaped cells. The clinical presentations, histological features, differential diagnosis, treatment options, and a literature review are presented.