GIANT CELL TUMOR IN SINUS MAXILLARY AND NASAL CAVITY: A RARE CASE REPORT

Abstract

A 33-year-old male patient attended a surgical service reporting a swelling in the right nasal cavity for around 6 months. Magnetic resonance imaging showed a hypointense image on the upper wall of the right maxillary sinus invading the nasal cavity of the same side. There was a previous biopsy in the same region with an inconclusive diagnosis. The patient was submitted to excisional biopsy, and the surgical specimen was referred for a pathologic service with clinical suspicion of paraganglioma. Histopathologic examination evidenced a lesion characterized by proliferation of vascular spaces and fibroblastic cells with discrete collagen fibers and areas of hemorrhage surrounded by a large number of multinucleated giant cells, some with disorganized nuclei and others similar to Touton giant cells. A large proliferation of xanthomatous-looking cells was also observed. The diagnosis of giant cell tumor was established. Currently the patient is under follow-up with no signs of relapse. A 33-year-old male patient attended a surgical service reporting a swelling in the right nasal cavity for around 6 months. Magnetic resonance imaging showed a hypointense image on the upper wall of the right maxillary sinus invading the nasal cavity of the same side. There was a previous biopsy in the same region with an inconclusive diagnosis. The patient was submitted to excisional biopsy, and the surgical specimen was referred for a pathologic service with clinical suspicion of paraganglioma. Histopathologic examination evidenced a lesion characterized by proliferation of vascular spaces and fibroblastic cells with discrete collagen fibers and areas of hemorrhage surrounded by a large number of multinucleated giant cells, some with disorganized nuclei and others similar to Touton giant cells. A large proliferation of xanthomatous-looking cells was also observed. The diagnosis of giant cell tumor was established. Currently the patient is under follow-up with no signs of relapse.