Giant cell lesions: A diagnostic mystery, case report and review of literature

Abstract

Giant cell lesions is a broad term encompassing a wide range of lesions that are biologically and morphologically diverse with an uncertain aetiology, whether it is a benign tumour, reactive lesion, inflammatory lesion or a self-healing lesion is ill understood. Their relation to each other also is not very clearly defined as they differ in their clinical and radiographic characteristics and their only similarity is in the histologic finding of non-neoplastic osteoclast like giant cells of different lineage. Owing to this fact their exact diagnosis continues to be one of the most obscure making them a dilemma, leaving many questions regarding their treatment and prognosis unanswered. Here we present a case of Central Giant Cell Tumor that was misdiagnosed as fibrous dysplasia that lead to an elusive treatment plan.