Abstract
Fever of unknown (FUO) origin challenging clinical condition. The causes of FUO are diverse: possible etiologies include infectious diseases, chronic granulomatous diseases, malignity, connective tissue disorders and vasculitis. Giant cell arteritis which affects the aorta and its main branches, contributes up to 17% of cases with fever of unknown origin above age 50. There is increasing evidence for a role for18F-FDG PET/CT in the diagnosis of vasculitis and18F-FDG PET/CT is a useful technic for evaluation of the FUO. Clinical studies show that FDG-PET is a useful diagnostic aid in obscure cases of fever of unknown origin. We report here a case of a 54-year-old woman who present to our clinic with FUO due to giant cell vasculitis.
Highlights
Fever of unknown origin is defined as a temperature higher than 38.3 ̊C that lasts for more than three weeks with no obvious source despite one week of inpatient investigation
Giant cell arteritis which affects the aorta and its main branches, contributes up to 17% of cases with fever of unknown origin above age 50
We present a case of giant cell arteritis diagnosed by Positron emission tomography (PET)-CT in a patient with fever of unknown origin
Summary
Fever of unknown origin is defined as a temperature higher than 38.3 ̊C that lasts for more than three weeks with no obvious source despite one week of inpatient investigation. Fever of unknown (FUO) origin challenges clinical condition. The causes of FUO are diverse: possible etiologies include infectious diseases, chronic granulomatous diseases, malignity, connective tissue disorders and vasculitis. There is increasing evidence for a role for 18FFDG PET/CT in the diagnosis of vasculitis and 18FFDG PET/CT is a useful technic for evaluation of the FUO.
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